Current evidence suggests that some people may be more susceptible to contracting an immune or inflammatory reaction when exposed to certain metals in implanted devices. Symptoms can be limited to the region where the device is or more generalized. Reported systemic symptoms include weakness, fatigue, rash and joint or muscle pain.
The FDA is hosting a meeting to discuss immune responses to metal-containing implants and dental amalgams Nov. 13-14, asking the public to determine crucial gaps in the current science and what FDA approaches should be considered.
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