The retrospective cohort study was conducted on patients treated with dental implants from 2007 to 2013. A total of 916 dental implants in 490 patients, including 94 implants on 51 patients using selective serotonin reuptake inhibitors, were included in the analysis.
The study found that inhibitor usage was associated with an increased risk of dental implants failure as compared with non-users of the inhibitors. The failure rates were 4.6 percent for non-users of selective serotonin reuptake inhibitors and 10.6 percent for selective serotonin reuptake inhibitors users. Also, small implant diameters, bone augmentation and smoking habits also seemed to be associated with higher risk of implant failure.
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